Jazz Pharmaceuticals plc (NASDAQ: JAZZ) has submitted an application for Food and Drug Administration (FDA) approval of JZP-258, a new drug for cataplexy and excessive daytime sleepiness (EDS) in patients with narcolepsy age 7 and up. To speed along an FDA review of JZP-258, the company is redeeming a priority review voucher that shortens the FDA's decision timeline from 10 months to six months. Image source: Getty Images. The loss of muscle tone while conscious, or cataplexy, and EDS are two of the five primary symptoms of narcolepsy. EDS affects every patient, while roughly 70% of patients experience cataplexy. If approved, JZP-258 could become an important treatment option, particularly in patients on a sodium-restricted diet due to cardiovascular disease or hypertension. Cardiometabolic comorbidities, including obesity and hypertension, are common in narcolepsy, so many people aren't prescribed Jazz Therapeutics' existing blockbuster narcolepsy drug, Xyrem, which is formulated with sodium. JZP-258 contains the same active ingredient as Xyrem; however, it uses non-sodium cations, including calcium, magnesium, and potassium, in its formulation to reduce sodium levels by 92%. Jazz Pharmaceuticals estimates that fewer than 50% of U.S. narcolepsy patients, or 75,000 people, are diagnosed and currently being treated. At the JP Morgan Healthcare Conference earlier this month, Jazz Pharmaceuticals indicated it expects an FDA decision during the third quarter. If JZP-258 is approved, then the company's plan is to begin marketing it as early as the fourth quarter of 2020. 10 stocks we like better than Jazz PharmaceuticalsWhen investing geniuses David and Tom Gardner have a stock tip, it can pay to listen. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.* David and Tom just revealed what they believe are the ten best stocks for investors to buy right now... and Jazz Pharmaceuticals wasn't one of them! That's right -- they think these 10 stocks are even better buys. See the 10 stocks *Stock Advisor returns as of December 1, 2019 Todd Campbell has no position in any of the stocks mentioned. His clients may have positions in the companies mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.Source